The heart of the neural crest: cardiac neural crest cells in development and regeneration
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چکیده
منابع مشابه
A novel role for cardiac neural crest in heart development.
It is well known that cardiac neural crest participates in development of the cardiac outflow septation and patterning of the great arteries. Less well known is that ablation of the cardiac neural crest leads to a primary myocardial dysfunction. Recent data suggests that the myocardial dysfunction occurs because of the absence of an interaction of neural crest and pharyngeal endoderm to alter s...
متن کاملFate of the mammalian cardiac neural crest.
A subpopulation of neural crest termed the cardiac neural crest is required in avian embryos to initiate reorganization of the outflow tract of the developing cardiovascular system. In mammalian embryos, it has not been previously experimentally possible to study the long-term fate of this population, although there is strong inference that a similar population exists and is perturbed in a numb...
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To establish whether a region of the cranial neural crest contributes cells to the developing heart of Ambystoma mexicanum (axolotl), as it does in many other vertebrates, we constructed a fate map for the neural crest in late neurula stage (stage 19-20) embryos. The fluorescent vital dye, DiI, was used as the lineage label. The various regions of the cranial neural folds were identified in rel...
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The tooth is a vertebrate-specific organ that deve]ops through a series of reciprocal interactions between epithelium and mesenchyme. In this process, the neural crest (NC) cells participate in tooth development. NC cells are multipotent cells that are generated from the IHteral ridge of the dorsal neural tube during the early stuges of embryogenesis. NC cells migrate into various tissues, wher...
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The neural crest is an intriguing cell population that gives rise to many derivatives which are all generated far from their final destinations. From its induction to the delamination of the cells, multiple signalling pathways converge to regulate the expression of effector genes, the products of which endow the cells with invasive and migratory properties reminiscent of those displayed by mali...
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ژورنال
عنوان ژورنال: Development
سال: 2020
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.188706